ZFIN ID: ZDB-FIG-170526-25
Aksoy et al., 2017 - Personalized genome sequencing coupled with iPSC technology identifies GTDC1 as a gene involved in neurodevelopmental disorders. Human molecular genetics   26:367-382 Full text @ Hum. Mol. Genet.
EXPRESSION / LABELING:
Genes:
Fish:
Knockdown Reagent:
Anatomical Terms:
Stage: Long-pec
PHENOTYPE:
Fish:
Knockdown Reagent:
Observed In:
Stage: Long-pec

Fig. 5 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
fgfr3 AB standard conditions Long-pec hindbrain ISH
Long-pec midbrain ISH
Long-pec telencephalon ISH
AB + MO1-gtdc1 standard conditions Long-pec hindbrain ISH
Long-pec midbrain ISH
Long-pec telencephalon ISH
isl1a AB standard conditions Long-pec forebrain ISH
Long-pec hypothalamus ISH
Long-pec retinal ganglion cell ISH
AB + MO1-gtdc1 standard conditions Long-pec forebrain ISH
Long-pec hypothalamus ISH
Long-pec Not Detected retinal ganglion cell ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
AB + MO1-gtdc1 standard conditions Long-pec embryo development disrupted, abnormal
Long-pec eye decreased size, abnormal
Long-pec forebrain isl1a expression decreased amount, abnormal
Long-pec head decreased size, abnormal
Long-pec hypothalamus isl1a expression decreased amount, abnormal
Long-pec retinal ganglion cell isl1a expression absent, abnormal
Long-pec trunk curved, abnormal
knu3Tg + MO1-gtdc1 standard conditions Long-pec optic tectum neuron increased amount, abnormal
Full text @ Hum. Mol. Genet.