ZFIN ID: ZDB-FIG-170516-5
Yang et al., 2016 - RNA polymerase II pausing differentially regulates signaling pathway genes to control hematopoietic stem cell emergence in zebrafish. Blood   128(13):1701-10 Full text @ Blood
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Conditions:
Anatomical Terms:
Stage Range: Prim-25 to Long-pec
PHENOTYPE:
Fish:
Conditions:
Observed In:
Stage Range: Prim-25 to Long-pec

Fig. 5 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
DsRed la401Tg ; la2Tg control Prim-25 ventral wall of dorsal aorta hematopoietic stem cell IFL
la401Tg ; la2Tg chemical treatment: LY-2157299 Prim-25 ventral wall of dorsal aorta hematopoietic stem cell IFL
la401Tg ; la2Tg ; supt5hm806/m806 control Prim-25 ventral wall of dorsal aorta hematopoietic stem cell IFL
la401Tg ; la2Tg ; supt5hm806/m806 chemical treatment: LY-2157299 Prim-25 ventral wall of dorsal aorta hematopoietic stem cell IFL
EGFP la2Tg control Long-pec intermediate cell mass of mesoderm hematopoietic multipotent progenitor cell IHC
la2Tg chemical treatment: LY-2157299 Long-pec intermediate cell mass of mesoderm hematopoietic multipotent progenitor cell IHC
la2Tg ; supt5hm806/m806 control Long-pec intermediate cell mass of mesoderm hematopoietic multipotent progenitor cell IHC
la2Tg ; supt5hm806/m806 chemical treatment: LY-2157299 Long-pec intermediate cell mass of mesoderm hematopoietic multipotent progenitor cell IHC
la401Tg ; la2Tg control Prim-25 ventral wall of dorsal aorta hematopoietic stem cell IFL
la401Tg ; la2Tg chemical treatment: LY-2157299 Prim-25 ventral wall of dorsal aorta hematopoietic stem cell IFL
la401Tg ; la2Tg ; supt5hm806/m806 control Prim-25 ventral wall of dorsal aorta hematopoietic stem cell IFL
la401Tg ; la2Tg ; supt5hm806/m806 chemical treatment: LY-2157299 Prim-25 ventral wall of dorsal aorta hematopoietic stem cell IFL
runx1 WT control Prim-25 hematopoietic multipotent progenitor cell ISH
WT chemical treatment: LY-2157299 Prim-25 hematopoietic multipotent progenitor cell ISH
WT chemical treatment: SB 505124 Prim-25 hematopoietic multipotent progenitor cell ISH
fb6Tg control Prim-25 hematopoietic multipotent progenitor cell ISH
fb6Tg heat shock Prim-25 hematopoietic multipotent progenitor cell ISH
supt5hm806/m806 control Prim-25 hematopoietic multipotent progenitor cell ISH
supt5hm806/m806 chemical treatment: LY-2157299 Prim-25 hematopoietic multipotent progenitor cell ISH
supt5hm806/m806 chemical treatment: SB 505124 Prim-25 hematopoietic multipotent progenitor cell ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
fb6Tg heat shock Prim-25 hematopoietic multipotent progenitor cell runx1 expression decreased amount, abnormal
Prim-25 hematopoietic multipotent progenitor cell decreased amount, abnormal
Prim-25 hematopoietic progenitor cell differentiation decreased occurrence, abnormal
la2Tg ; supt5hm806/m806 control Long-pec hematopoietic multipotent progenitor cell cell population proliferation decreased occurrence, abnormal
Long-pec hematopoietic multipotent progenitor cell decreased amount, abnormal
Long-pec intermediate cell mass of mesoderm hematopoietic multipotent progenitor cell EGFP expression decreased amount, abnormal
la2Tg ; supt5hm806/m806 chemical treatment: LY-2157299 Long-pec hematopoietic multipotent progenitor cell amount, ameliorated
Long-pec hematopoietic multipotent progenitor cell cell population proliferation occurrence, ameliorated
Long-pec intermediate cell mass of mesoderm hematopoietic multipotent progenitor cell EGFP expression amount, ameliorated
la401Tg ; la2Tg ; supt5hm806/m806 control Prim-25 hematopoietic stem cell differentiation decreased occurrence, abnormal
Prim-25 ventral wall of dorsal aorta hematopoietic stem cell decreased amount, abnormal
Prim-25 ventral wall of dorsal aorta hematopoietic stem cell DsRed expression decreased amount, abnormal
Prim-25 ventral wall of dorsal aorta hematopoietic stem cell EGFP expression decreased amount, abnormal
la401Tg ; la2Tg ; supt5hm806/m806 chemical treatment: LY-2157299 Prim-25 hematopoietic stem cell differentiation occurrence, ameliorated
Prim-25 ventral wall of dorsal aorta hematopoietic stem cell amount, ameliorated
Prim-25 ventral wall of dorsal aorta hematopoietic stem cell DsRed expression amount, ameliorated
Prim-25 ventral wall of dorsal aorta hematopoietic stem cell EGFP expression amount, ameliorated
supt5hm806/m806 control Prim-25 hematopoietic multipotent progenitor cell runx1 expression decreased amount, abnormal
Prim-25 hematopoietic multipotent progenitor cell decreased amount, abnormal
Prim-25 hematopoietic progenitor cell differentiation decreased occurrence, abnormal
supt5hm806/m806 chemical treatment: LY-2157299 Prim-25 hematopoietic multipotent progenitor cell runx1 expression amount, ameliorated
Prim-25 hematopoietic multipotent progenitor cell amount, ameliorated
Prim-25 hematopoietic progenitor cell differentiation occurrence, ameliorated
supt5hm806/m806 chemical treatment: SB 505124 Prim-25 hematopoietic multipotent progenitor cell runx1 expression amount, ameliorated
Prim-25 hematopoietic multipotent progenitor cell amount, ameliorated
Prim-25 hematopoietic progenitor cell differentiation occurrence, ameliorated
Full text @ Blood