FIGURE

Fig. 10

ID

ZDB-FIG-170224-16

Publication

Hamm et al., 2016 - Sema3d controls collective endothelial cell migration by distinct mechanisms via Nrp1 and PlxnD1

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Fig. 10

Collective migration and cell morphology of the LLP are impaired in sema3d morphants. (A) Sema3d antibody staining and in situ hybridization (ISH) for sema3d showed Sema3d expression in the LLP and its deposited neuromasts (white arrowheads). (B) LLP migration distance is reduced in sema3d morphants at 24 and 30 hpf in Tg(-8.0cldnb:lynEGFP)zf106 embryos (LLP indicated by white arrowheads). (C) Deposition of neuromasts (pink arrowhead) is impaired in sema3d morphants at 30 hpf. (D) Organized LLP rosette structure (pink arrowheads) and cell morphology are impaired in sema3d morphants at 24 and 30 hpf.

Expression Data

Genes:	EGFP sema3d
Antibody:	Ab1-sema3d
Fish:	WT zf106Tg zf106Tg + MO2-sema3d
Knockdown Reagent:	MO2-sema3d
Anatomical Terms:	posterior lateral line neuromast posterior lateral line primordium
Stage Range:	Prim-5 to Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	zf106Tg + MO2-sema3d
Knockdown Reagent:	MO2-sema3d
Observed In:	posterior lateral line neuromast primordium migration posterior lateral line primordium
Stage Range:	Prim-5 to Prim-15

Phenotype Detail

Acknowledgments

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