ZFIN ID: ZDB-FIG-170216-2
Kopajtich et al., 2016 - Biallelic IARS Mutations Cause Growth Retardation with Prenatal Onset, Intellectual Disability, Muscular Hypotonia, and Infantile Hepatopathy. American journal of human genetics   99(2):414-22 Full text @ Am. J. Hum. Genet.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Fish:
Anatomical Terms:
Stage Range: 5-9 somites to Long-pec
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage: Prim-5

Fig. 3 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
iars1 WT control 5-9 somites neural rod ISH
5-9 somites somite ISH
Prim-5 cerebellum ISH
Prim-5 optic tectum ISH
Prim-5 somite ISH
Long-pec epiphysis ISH
Long-pec hindbrain ISH
Long-pec optic tectum ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO2-iars standard conditions Prim-5 brain deformed, abnormal
Prim-5 hatching decreased process quality, abnormal
Prim-5 whole organism viability, abnormal
Prim-5 whole organism anterior-posterior axis decreased length, abnormal
WT + MO3-iars standard conditions Prim-5 brain deformed, abnormal
Prim-5 hatching decreased process quality, abnormal
Prim-5 whole organism viability, abnormal
Prim-5 whole organism anterior-posterior axis decreased length, abnormal
Full text @ Am. J. Hum. Genet.