FIGURE

Fig. 3

ID

ZDB-FIG-170131-15

Publication

Zhou et al., 2016 - PEG-b-PCL polymeric nano-micelle inhibits vascular angiogenesis by activating p53-dependent apoptosis in zebrafish.

Other Figures

All Figure Page

Back to All Figure Page

Fig. 3

Figure 3 Effects of PEG-b-PCL on zebrafish embryos and larva.
Notes: (A) The mortality rates of embryos exposed to 0, 60, 120, and 240 μg/mL PEG-b-PCL nano-micelles. (B) Representative images showing the morphological changes of embryos exposed to different doses of nano-micelle at indicated stages. Red arrowheads indicate pericardial edema, black arrowheads indicate yolk sac deformation, and blue arrowheads indicate tail curve. (C) Quantification of 72 hpf embryos showing malformations, including pericardial edema, yolk sac deformation, and tail curve. Data are expressed as mean ± SEM from three independent experiments (n=180), *P<0.05, **P<0.01.
Abbreviations: hpf, hours postfertilization; PEG-b-PCL, poly(ethylene glycol)-b-poly(ε-caprolactone); SEM, standard error of mean.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Nanomedicine