FIGURE

Fig. 2

ID

ZDB-FIG-161129-4

Publication

Widziolek et al., 2016 - Zebrafish as a new model to study effects of periodontal pathogens on cardiovascular diseases

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Fig. 2

Effect of wild-type Pg W83 on zebrafish larvae tissue structure.

Lateral view of impaired, elongated heart morphology of Pg W83-infected larvae; white arrowhead indicates heart. Heart chambers were distant and much smaller in comparison to PBS-injected control larvae (a). Sagittal histological sections of H&E stained 48 hpi Pg W83-infected larvae revealing advanced tissue damage in the cranial and cardiac regions along with yolk sac oedemas (b). In all figures larvae were infected with 5 × 10⁴CFU Pg at 30 hpf W83 or PBS as a control. At least three individual experiments were performed and images are representative of at least n = 5 larvae per group in each experiment. Scale bars = 100 μm in (a) and 200 μm in (b).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT
Condition:	bacterial treatment by injection: Porphyromonas gingivalis W83
Observed In:	atrium cardiac ventricle head heart pericardium yolk
Stage Range:	Long-pec to Day 4

Phenotype Detail

Acknowledgments

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