FIGURE

Fig. S1

ID
ZDB-FIG-161118-5
Publication
Tang et al., 2016 - Loss of a Candidate Biliary Atresia Susceptibility Gene, add3a, Causes Biliary Developmental Defects in Zebrafish
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Fig. S1

Documentation of morpholino effect. (A-B) Quantitative PCR expression of product with 3' primer in deleted exon, showing markedly decreased expression of add3a (A) and xpnpep1 (B). (C) Gallbladder PED-6 uptake from control, add3a MO-injected, and add3a MO and mRNA-injected larvae, showing statistically significant rescue of the add3a MO phenotype by add3a mRNA injection. (D) Confocal projection of liver cytokeratin staining of mRNA-rescued 5 dpf larva, showing an essentially normal phenotype. *p≤0.0001, chi square test, MO- + mRNA-injected vs. MO-injected.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Pediatr. Gastroenterol. Nutr.