FIGURE

Fig. 3

ID

ZDB-FIG-160928-22

Publication

Mercatali et al., 2016 - Development of a Patient-Derived Xenograft (PDX) of Breast Cancer Bone Metastasis in a Zebrafish Model

Other Figures

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Fig. 3

Images of carboxyfluorescein succinimidyl ester (CFSE)-labeled, patient-derived breast cancer bone metastasis (primary cells) xenografted in Tg(kdrl:mcherry) ZF embryos. (A) Whole-body image of the zebrafish embryo at 5 dpi (25× magnification). Primary cells disseminated predominantly in the caudal hematopoietic tissues (CHT) of the embryo; (B) Details of (A), showing the interactions of primary cells with the zebrafish vessels in the CHT. Cells extravasated in the CHT of the ZF embryo and engrafted in close proximity of the vessels. Fluorescent images merged with brightfield image, 63× magnification; (C) Combined picture of the CHT of embryo in (A,B). Individual images were taken at 63× magnification.

Expression Data

Gene:	mCherry
Fish:	s916Tg
Condition:	cancer xenotransplantation
Anatomical Term:	vasculature
Stage:	Days 7-13

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Mol. Sci.