FIGURE

Fig. 6

ID

ZDB-FIG-160706-46

Publication

Kawase et al., 2016 - EP300 Protects from Light-Induced Retinopathy in Zebrafish

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Fig. 6

Inhibition of EP300 increases BrdU incorporation in putative Müller cells in the zebrafish model of light-induced retinopathy. (A) Protocol for light-induced retinal damage in larval zebrafish, as described for Figure 4A. After light exposure, whole-mount immunohistochemical staining with anti-BrdU antibody was performed. (B) Representative images of anti-BrdU antibody staining of zebrafish exposed to normal or intense light. Scale bars, 100 µm. (C) Quantitative analysis of BrdU-positive cells in the retinas of zebrafish exposed to the conditions shown in (B). *p < 0.05. Data are the mean ± SEM of n = 8 for all groups.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	slc45a2^b4/b4
Condition:	chemical treatment: C646, high light intensity
Observed In:	Muller cell cell population proliferation
Stage:	Day 6

Phenotype Detail

Acknowledgments

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