FIGURE

Fig. S4

ID
ZDB-FIG-160525-32
Publication
Zhao et al., 2016 - An essential role for Grk2 in Hedgehog signalling downstream of Smoothened
Other Figures
All Figure Page
Back to All Figure Page
Fig. S4

MZgrk2 is fully rescued by mRNA encoding Grk2K220R and Grk2 domain swapping assay

A. In situ hybridisation of ptch2 and nkx2.2a in 24hpf wildtype (left column) and MZgrk2 embryos expressing Grk2K220RGFP (right column) (n = 30 for each sample). Scale bar, 200 µm.

B. Prox1a (green) and Eng (red) expression in the myotome of 30hpf MZgrk2 embryos injected with mRNA encoding Grk2ΔRGSGFP, Grk2ΔkinaseGFP, Grk2ΔPHGFP, Grk2ΔCmarginGFP and Grk2ΔNmarginGFP. Merge images show nuclei labelled with DAPI (blue) (n = 20). Scale bar, 50 µm.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ EMBO Rep.