FIGURE

Fig. 2 S2

ID

ZDB-FIG-160525-17

Publication

Deshwar et al., 2016 - The Apelin receptor enhances Nodal/TGFβ signaling to ensure proper cardiac development

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Fig. 2 S2

Aplnr activation enhances Nodal target gene expression.

(A-I) Expression of the canonical Nodal target genes gsc, flh and sox32 in WT (A-C), aplnrb RNA injected embryos (D-F) and embryos treated with the Aplnr agonist ML233 (G-I) at 8 hpf. Embryos are viewed from the dorsal side with anterior to the top. (J-O) Expression of the canonical Nodal target genes gsc, flh and sox32 in aplnra/b morphant embryos with or without ML233 at 8 hpf. Embryos are viewed from the dorsal side with anterior to the top. (P-U) Expression of the canonical Nodal target genes gsc, flh and sox32 in oep morphant embryos with or without the injection of aplnrb RNA and addition of ML233 at 8 hpf. Embryos are viewed from the dorsal side with anterior to the top.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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