FIGURE

Fig. 7

ID

ZDB-FIG-160505-11

Publication

Han et al., 2016 - Trim69 regulates zebrafish brain development by ap-1 pathway

Other Figures

All Figure Page

Back to All Figure Page

Fig. 7

Loss of c-Jun rescued the deformed brain and apoptosis induced by trim69 knockdown.

(A) Loss of c-Jun rescued the deformed brain induced by trim69 knockdown. trim69-CON(a): control group; trim69-MO(b): trim69 knocking down; trim69-MO:c-Jun-MO(c): co-injection with trim69-MO and c-Jun-MO; black arrow indicates mid-hind brain boundary(MHB); scale bar: 200 µm; (d) Statistical analysis of the zebrafish embryo phenotype. Normal: the phenotype of the zebrafish embryo is normal; deformed: the phenotype of the zebrafish embryo phenotype is abnormal. (B) The examined apoptosis of zebrafish embryos by TUNEL assay. trim69-CON(e): control group; trim69-MO(f): trim69 knocking down; trim69-MO:cJun-MO(g): co-injection with trim69-MO and c-Jun-MO; black arrow indicates apoptotic cells; scale bar: 200 µm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-trim69 WT + MO1-trim69 + MO2-jun
Knockdown Reagents:	MO1-trim69 MO2-jun
Observed In:	apoptotic process brain brain development midbrain hindbrain boundary
Stage:	Prim-5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Sci. Rep.