ZFIN Image: Han et al., 2016, Fig. 7

Image

Figure Caption

Fig. 7

Loss of c-Jun rescued the deformed brain and apoptosis induced by trim69 knockdown.

(A) Loss of c-Jun rescued the deformed brain induced by trim69 knockdown. trim69-CON(a): control group; trim69-MO(b): trim69 knocking down; trim69-MO:c-Jun-MO(c): co-injection with trim69-MO and c-Jun-MO; black arrow indicates mid-hind brain boundary(MHB); scale bar: 200 µm; (d) Statistical analysis of the zebrafish embryo phenotype. Normal: the phenotype of the zebrafish embryo is normal; deformed: the phenotype of the zebrafish embryo phenotype is abnormal. (B) The examined apoptosis of zebrafish embryos by TUNEL assay. trim69-CON(e): control group; trim69-MO(f): trim69 knocking down; trim69-MO:cJun-MO(g): co-injection with trim69-MO and c-Jun-MO; black arrow indicates apoptotic cells; scale bar: 200 µm.

Figure Data

Phenotype details

Acknowledgments

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