FIGURE

Fig. 4

ID

ZDB-FIG-160407-14

Publication

Zhang et al., 2016 - A Naturally-Derived Compound Schisandrin B Enhanced Light Sensation in the pde6c Zebrafish Model of Retinal Degeneration

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Fig. 4

Photoreceptor morphology in the pde6c^w59 retinas with and without SchB treatment.Whole-mount immunostaining was conducted to evaluate the effect of SchB treatment on rods (A-C) and cones (D-F) in the pde6c^w59 mutants. The rods were immunostained with anti-4c12 [22], whereas the red-green double cones were immunostained with anti-zpr1 [41]. In (A-C), a central-medial region of the retina is shown, and the optic nerve is highlighted by a dotted circle. In (D-F), the medial view of the whole retina is shown, and the optic nerve is indicated by a yellow asterisk. In all figures, dorsal is to the top. Scale bars = 50 µm.

Expression Data

Antibodies:	Ab-4C12 zpr-1
Fish:	WT pde6c^w59/w59
Condition:	chemical treatment: (+)-schisandrin B
Anatomical Terms:	green sensitive photoreceptor cell red sensitive photoreceptor cell retinal cone cell retinal rod cell
Stage:	Day 6

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	pde6c^w59/w59
Condition:	chemical treatment: (+)-schisandrin B
Observed In:	retinal cone cell retinal rod cell visual behavior
Stage:	Day 6

Phenotype Detail

Acknowledgments

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