FIGURE

Fig. 5

ID

ZDB-FIG-160316-17

Publication

Yoshimatsu et al., 2016 - Presynaptic partner selection during retinal circuit reassembly varies with timing of neuronal regeneration in vivo

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Fig. 5

H3 HCs synapse with blue cones and other cone types when ultraviolet cones fail to regenerate.

(a) Schematic showing period of metronidazole (Met) treatment (red lines) and ultraviolet-cone presence in the retina (magenta bars). Images show distribution of ultraviolet (magenta) and blue (cyan) cones in the whole-mount retina at the end of the treatments. (b) Examples of an H3 HC in control retina, in a retina with no ultraviolet regeneration (No UV Reg.) and in a retina with delayed regeneration (Delayed UV Reg.). Inset for the no regeneration example shows sideview of a dendritic tip (arrowhead) in the boxed region contacting a zpr1-positive red or green cone (R/G, shown in red). Inset for the delayed regeneration example shows contact with a new (EdU⁺, green) ultraviolet cone. (c,d) Measurements across H3 HC populations; circles are measurements from individual cells. Error bars are s.e.m. Mann-Whitney rank-sum test. (e) Comparison of the number of ultraviolet- versus blue-cone contacts for individual H3 cells in control and regenerated conditions. UV, ultraviolet. B, blue.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Nat. Commun.