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Research
General Information
ZIRC
ZFIN ID: ZDB-FIG-160208-2
Guimier et al., 2015 - MMP21 is mutated in human heterotaxy and is required for normal left-right asymmetry in vertebrates. Nature Genetics   47(11):1260-3 Full text @ Nat. Genet.
EXPRESSION / LABELING:
Gene:
Fish:
Anatomical Term:
Stage: 5-9 somites
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage: Long-pec

Fig. 2 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
mmp21 AB standard conditions 5-9 somites Kupffer's vesicle ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
AB + MO1-mmp21 standard conditions Long-pec determination of heart left/right asymmetry process quality, abnormal
Long-pec heart position, abnormal
Long-pec heart looping process quality, abnormal
Long-pec left/right pattern formation process quality, abnormal
AB + MO3-mmp21 standard conditions Long-pec determination of heart left/right asymmetry process quality, abnormal
Long-pec heart position, abnormal
Long-pec heart looping process quality, abnormal
Long-pec left/right pattern formation process quality, abnormal
twu34Tg + MO1-mmp21 standard conditions Long-pec determination of heart left/right asymmetry process quality, abnormal
Long-pec heart position, abnormal
Long-pec heart looping process quality, abnormal
Long-pec left/right pattern formation process quality, abnormal
twu34Tg + MO3-mmp21 standard conditions Long-pec determination of heart left/right asymmetry process quality, abnormal
Long-pec heart position, abnormal
Long-pec heart looping process quality, abnormal
Long-pec left/right pattern formation process quality, abnormal
Full text @ Nat. Genet.