FIGURE

Fig. 3 S1

ID

ZDB-FIG-160205-37

Publication

Hesse et al., 2015 - The human ARF tumor suppressor senses blastema activity and suppresses epimorphic tissue regeneration

Other Figures

(all 15)

All Figure Page

Back to All Figure Page

Fig. 3 S1

Analysis of ARF expression in zebrafish cells. (A) Immunofluorescence for Mdm2 and ARF (top) and Tp53 (bottom) in zebrafish cells (ZKS) transfected with pcDNA-ARF. ARF and Mdm2 co-localize in the nucleolus (arrow) when ARF is expressed; in cells without ARF, Mdm2 has a diffuse nuclear staining pattern (arrow head; top). Tp53 upregulation depends on ARF expression (bottom). Scale bars: 10 µm. (B) Quantification of Tp53 upregulation in zebrafish cells (ZKS) transfected with pcDNA-ARF (N = 100, p<0.01). Results are shown as mean ± standard deviation.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Elife