FIGURE

Fig. 3

ID

ZDB-FIG-160120-13

Publication

Starr et al., 2004 - Mutation of the zebrafish choroideremia gene encoding Rab escort protein 1 devastates hair cells

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Fig. 3

Analysis of hair-cell function in WT and mutant fish at 7 dpf. While a vibratory stimulus (200 Hz, ±2 µm; Bottom) was provided by a glass probe, extracellular microphonic potentials were recorded and averaged over 50-100 stimulus epochs. The WT larvae displayed a robust electrical response at twice the stimulus frequency (Top), reflecting the activation of two populations of hair cells with opposing orientations. No response to the vibratory stimulus was seen in the 10 mutant larvae examined (Middle).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	chm^ru848/ru848
Observed In:	detection of mechanical stimulus involved in sensory perception of sound inner ear hair cell
Stage:	Days 7-13

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA