FIGURE

Fig. S8

ID

ZDB-FIG-160108-8

Publication

Tuttle et al., 2014 - Rabconnectin-3a regulates vesicle endocytosis and canonical Wnt signaling in zebrafish neural crest migration

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Fig. S8

Changes in downstream Wnt target gene expression. (A-H) In situ hybridization for Wnt target gene expression in wild-type and rbc3a-MO1-injected embryos. Dorsal views (A-F), lateral views (G, H). Several genes display reduced expression in the NC (arrowheads) in rbc3a-MO1-injected embryos from 10-12 hpf including gbx2 (A, B), snail2 (C, D), twist1a (E, F), and axin2 (G, H). Scale bar, 100 µm. (I) axin2, nmyc, and lef1 show decreased expression by 13 hpf in rbc3a-MO1-injected embryos. Error bars represent triplicate experiments ± SEM. * p<0.05.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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