FIGURE

Fig. 1

ID

ZDB-FIG-151130-23

Publication

Dhakal et al., 2015 - Abnormal retinal development in cloche mutant zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Fig. 1

Ocular abnormalities in cloche mutant embryos. A–F: Confocal images of kdrl:EGFP wild-type (A,C,E) and clo-/- (B,D,F) blood vessels (green). Hyaloid artery (ha) has invaded the eye and superficial vessels (sv) begin to form at 29 hpf in wild type (A) but not clo-/- (B). C,D: Hyaloid capillaries (hc), and superficial vasculature (sv) have developed at 54 hpf in wild-type (C) but not clo-/- (D). E,F: Branchial arch vessels (bav) are present at 54 hpf in wild-type (E), and are strongly reduced in clo-/- (F). G,H: Confocal images of Fast Red staining of endogenous alkaline phosphatase; focal plane of hyaloid capillaries, which are present in wild-type (G) but not clo-/- (H). I-L: Live, wild-type (I, K) and clo-/- (J,L) embryos imaged at 36 hpf (I,J) and 48 hpf (K,L). M–P: Eye diameters and lens diameters of wild-type and clo-/- embryos at 30 (M), 36 (N), 48 (O) and 72 (P) hpf; ***P < 0.001. Scale bars = 50 µm in A (applies to A,B); in C (applies to (C–F); in G (applies to G,H).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dev. Dyn.