FIGURE

Fig. 3

ID

ZDB-FIG-151029-48

Publication

Mosimann et al., 2015 - Chamber identity programs drive early functional partitioning of the heart

Other Figures

All Figure Page

Back to All Figure Page

Fig. 3

Lack of endocardial signals does not affect integration of FHF with SHF.

(a,b) Anterior (a) and tail region (b) expression of drl:EGFP in wild-type zebrafish at 24–28 h.p.f., scale bar, 50 µm; note the circulating red blood cells. (c,d) Anterior (c) and tail region (d) drl:EGFP expression at 24–28 h.p.f. in the recessive zebrafish mutant cloche, which lacks all endothelial and haematopoietic lineages; scale bar, 50 µm; note the formation of linear heart tube in cloche (solid arrowhead in c and residual angioblasts in the tail (d). (e,f) Top-down 2-µm confocal projection of 56 h.p.f. cloche mutant heart, drl:EGFP expression counter stained with anti-GFP (e, green in f) and cardiomyocytes stained with myosin/MF20 (red in f); scale bar, 50 µm; note how despite missing endocardium the heart features both demarcated FHF and SHF myocardium, solid arrowhead in e indicates the distal ventricle region. Atrium (A) and ventricle (V) labelled in e.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Nat. Commun.