FIGURE

Fig. 5

ID

ZDB-FIG-151009-16

Publication

Rydeen et al., 2015 - Excessive feedback of Cyp26a1 promotes cell non-autonomous loss of retinoic acid signaling

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Fig. 5

Cyp26a1 is required for increased cardiac specification in VP-RAR expressing embryos. (A?D) ISH of nkx2.5 in embryos obtained from a gir^+/- adult cross with and without vp-rar mRNA injection. nkx2.5 expression is increased in vp-rar mRNA injected gir^+/? embryos compared to their uninjected siblings, while vp-rar mRNA injected gir^-/- embryos show no difference compared to uninjected gir^-/- siblings. (E) Quantification of nkx2.5 expression length. Asterisks indicate statistically different from control (p<0.05) using Student′s t-test.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 405(1), Rydeen, A., Voisin, N., D'Aniello, E., Ravisankar, P., Devignes, C.S., Waxman, J.S., Excessive feedback of Cyp26a1 promotes cell non-autonomous loss of retinoic acid signaling, 47-55, Copyright (2015) with permission from Elsevier. Full text @ Dev. Biol.