FIGURE

Fig. 1

ID
ZDB-FIG-150616-25
Publication
Zhang et al., 2015 - Pharmacological Characterization of an Antisense Knockdown Zebrafish Model of Dravet Syndrome: Inhibition of Epileptic Seizures by the Serotonin Agonist Fenfluramine
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Fig. 1

Morphology and larval locomotor activity of scn1Lab ATG morphants.

(A) Dorsal view of a representative 5 dpf CTRL MO-injected larva. (B) Dorsal view of a representative 5 dpf ATG MO-injected larva. (C) The y-axis depicts the total larval locomotor activity of ATG MO- compared to CTRL MO-injected larvae over a one-hour tracking experiment (30-minute integration time). Data were pooled from three independent experiments with 12 larvae per injection condition. Statistical analysis was performed using Mann-Whitney test. Error bars on all graphs represent the standard error of mean (SEM). *** P d 0.001.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Knockdown Reagent:
Observed In:
Stage Range: Protruding-mouth to Days 7-13

Phenotype Detail
Acknowledgments
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