FIGURE
Fig. 2
- ID
- ZDB-FIG-150505-4
- Publication
- Lin et al., 2015 - Angiopoietin-like proteins stimulate HSPC development through interaction with Notch receptor signaling
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Fig. 2
Angptls genetically interact with notch. (A) Notch eGFP Tg reporter embryos injected with angptls-MO (2 ng) had decreased notch activity in ISV (black arrowheads) and DA (red arrowhead) at 28hpf. (B) Overexpression of constitutively active notch in angptls-MO injected (2 ng) Tg(hsp70:Gal4;UAS:NICD) can restore cmyb-positive HSPCs (arrows) at 36hpf after heatshock. (C) Mib had no cmyb-positive HSPCs (arrows) at 36hpf compared to WT or het siblings. Overexpression of zangptl2 in mib by crossing Tg(hsp70:zangptl2) into mib can restore this defect upon heatshock. Scale bars: 50 µm. |
Expression Data
| Genes: | |
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| Fish: | |
| Condition: | |
| Knockdown Reagents: | |
| Anatomical Terms: | |
| Stage Range: | Prim-5 to Prim-25 |
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Condition: | |
| Knockdown Reagents: | |
| Observed In: | |
| Stage Range: | Prim-5 to Prim-25 |
Phenotype Detail
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