FIGURE

Fig. 3

ID

ZDB-FIG-150428-28

Publication

Sarmah et al., 2013 - Ethanol exposure disrupts extraembryonic microtubule cytoskeleton and embryonic blastomere cell adhesion, producing epiboly and gastrulation defects

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Fig. 3

Ethanol exposure affects radial intercalation and gastrulation cell movements.

(A,B) Confocal microscopy optical sections from the time-lapse image sequences at the most external epiblast layer of FITC-labeled histone-1 injected control (A) and ethanol (B) treated embryos at 4.5hpf. Solid white line highlights representative cells in the upper layer, dotted line indicates cell in the lower layer. (C,D) Schematic diagrams illustrating radial intercalation (RI) events in the control (C) and ethanol treated (D) embryos. Unlike control, ethanol treated cells showed lamellipodia extension in all directions. (E) Histogram showing RI events in the control and ethanol treated embryos. (F,G) The paths of ten deep cells in the mesendoderm of control and ethanol treated embryos. Cells in ethanol treated embryos showed abnormal trajectories. Animal pole, top; vegetal pole, bottom.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	TL
Condition:	chemical treatment by environment: ethanol
Observed In:	cell migration involved in gastrulation epiboly
Stage:	Shield

Phenotype Detail

Acknowledgments

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