FIGURE

Fig. S5

ID

ZDB-FIG-150319-29

Publication

Cheng et al., 2015 - The transcription factor hairy/E(spl)-related 2 induces proliferation of neural progenitors and regulates neurogenesis and gliogenesis

Other Figures

All Figure Page

Back to All Figure Page

Fig. S5

Her2 does not regulate neural patterning or neural versus epidermal fate determination. (A) Schematic illustration of a gastrula stage embryo in lateral view. Prospective tp63-positive epidermis is green; prospective otx2-positive and zic2b-positive neural ectoderm is magenta and blue, respectively. an, animal pole; D, dorsal; V, ventral; ve, vegetal pole. (B) The expression of otx2 and zic2b were downregulated by her2 MO and upregulated by her2 cRNA injections, as shown by in situ hybridization. (C) qPCR quantification for (B). (D) Quantification of the size of the otx2 or zic2b expression domain, showing no significant alterations from her2 cRNA or her2 MO injections. Alterations in Her2 expression had no significant effects on the expression of tp63. Region of interest was quantified by ImageJ *, p<0.05; **, p<0.01; n.s., not significant.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 397(1), Cheng, Y.C., Chiang, M.C., Shih, H.Y., Ma, T.L., Yeh, T.H., Huang, Y.C., Lin, C.Y., Lin, S.J., The transcription factor hairy/E(spl)-related 2 induces proliferation of neural progenitors and regulates neurogenesis and gliogenesis, 116-28, Copyright (2015) with permission from Elsevier. Full text @ Dev. Biol.