ZFIN Figure: Meireles et al., 2014, Fig. 2

ZFIN ID: ZDB-FIG-150219-11

ZFIN ID: ZDB-FIG-150219-11

Meireles et al., 2014 - The Phosphate Exporter xpr1b Is Required for Differentiation of Tissue-Resident Macrophages. Cell Reports 8(6):1659-67 Full text @ Cell Rep.

ADDITIONAL FIGURES

EXPRESSION / LABELING:

Genes:	apoeb mfap4
Fish:	xpr1b^st87/+; gl22Tg xpr1b^st87/st87; gl22Tg
Anatomical Terms:	brain macrophage microglial cell
Stage Range:	Long-pec to Protruding-mouth

PHENOTYPE:

Fish:	xpr1b^st87/st87; gl22Tg xpr1b^st87/st87; gl22Tg; y171Tg xpr1b^st87/st87; zf147Tg
Observed In:	brain macrophage brain microglial cell central nervous system macrophage trunk macrophage
Stage Range:	Long-pec to Days 7-13

Fig. 2 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details

Gene	Fish	Conditions	Stage	Qualifier	Anatomy	Assay
apoeb	xpr1b^st87/+; gl22Tg	standard conditions	Protruding-mouth		microglial cell	ISH
	xpr1b^st87/st87; gl22Tg	standard conditions	Protruding-mouth	Not Detected	brain microglial cell	ISH
mfap4	xpr1b^st87/+; gl22Tg	standard conditions	Long-pec to Protruding-mouth		brain macrophage	ISH
	xpr1b^st87/st87; gl22Tg	standard conditions	Long-pec to Protruding-mouth	Not Detected	brain macrophage	ISH

Antibody Labeling Details No data available

Phenotype Details

Fish	Conditions	Stage	Phenotype
xpr1b^st87/st87; gl22Tg	standard conditions	Long-pec - Day 4	central nervous system macrophage decreased amount, abnormal
		Long-pec - Day 4	trunk macrophage normal amount, normal
xpr1b^st87/st87; gl22Tg; y171Tg	standard conditions	Day 5	brain macrophage decreased amount, abnormal
xpr1b^st87/st87; zf147Tg	standard conditions	Day 5 - Days 7-13	brain microglial cell decreased amount, abnormal

Full text @ Cell Rep.