FIGURE

Fig. 5

ID

ZDB-FIG-150127-14

Publication

Hüsken et al., 2014 - Tcf7l2 Is Required for Left-Right Asymmetric Differentiation of Habenular Neurons

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Fig. 5

The Symmetric dHb Phenotype of tcf7l2 Mutants Is Epistatic to Parapineal Ablation

Dorsal views focused on the epithalamus of 2.5 dpf (A and A′) and 4 dpf (B–E′) embryos with anterior to the top.

(A and A′) The parapineal (pseudocolored red) is on the left in both wild-type and tcf7l2 mutant embryos.

(B–E′) In Et(gata2a:EGFP)^pku588; Tg(foxD3:GFP); Tg(flh:eGFP) triple-transgenic normal and parapineal-ablated embryos, dHbl neurons (green) and the pineal complex are labeled. The pineal is pseudocolored in blue and the parapineal and its projections in red (B–C′). Embryos as in (B)–(C′) were labeled for kctd12.1 subsequent to live imaging (D–E′).

Expression Data

Genes:	EGFP GFP kctd12.2
Fish:	WT tcf7l2^u754/u754 tcf7l2^u763/u763 pku588Et; u711Tg; zf104Tg u711Tg; zf104Tg
Anatomical Terms:	dorsal habenular nucleus epiphysis habenula parapineal organ
Stage Range:	Pec-fin to Day 4

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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