FIGURE

Fig. 2

ID

ZDB-FIG-150122-4

Publication

Zada et al., 2014 - Altered Behavioral Performance and Live Imaging of Circuit-Specific Neural Deficiencies in a Zebrafish Model for Psychomotor Retardation

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Fig. 2

The expression of TH-induced and HPT-axis genes in mct8-/- embryos. A. The expression pattern of klf9 in the forebrain (FB), midbrain (MB), and hindbrain (HB) of 6 dpf larvae (lateral view), as detected by whole-mount ISH. B. nrgna is predominantly expressed in the dorsal forebrain (DFB) and HB in 3 dpf embryo (dorsal view), as detected by whole-mount ISH. C. Relative mRNA expression levels of klf9 and nrgna in untreated and T3-treated WT embryos. D. Relative mRNA expression of klf9 and nrgna in 3 dpf mct8-/- and their WT-sibling embryos. E. Relative mRNA expression levels of tsh, trh, dio1, dio2, dio3, mct10, oatp1c1, thraa, thrab and thrb in 3 dpf mct8-/- and their WT-sibling embryos. Values represented as means±SEM (standard error of the mean). Statistical significance determined by t-test: two-sample assuming unequal variances followed by one-Sample Kolmogorov-Smirnov test.

Expression Data

Genes:	klf9 nrgna
Fish:	WT
Anatomical Terms:	forebrain forebrain dorsal region hindbrain midbrain
Stage Range:	Protruding-mouth to Day 6

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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