FIGURE

Fig. 3

ID

ZDB-FIG-150107-3

Publication

Maulding et al., 2014 - Mesodermal Fgf10b cooperates with other Fgfs during induction of otic and epibranchial placodes in zebrafish

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Fig. 3

fgf10b cooperates with fgf3 and fgf8 in otic induction. A-R: Live specimens at 27 hpf viewed at low magnification to show general morphology and high magnification to show otic vesicles; and dorsal views of in situ hybridizations to visualize pax2a in the otic placodes at 14 hpf. Genetic manipulations are indicated down the left side of the figure. Mean surface area (± standard deviation, n ≥ 8) of otic placodes and vesicles, normalized to wild-type control embryos, are indicated for each genotype/knockdown.

Expression Data

Gene:	pax2a
Fish:	WT fgf3^{t26212/t26212} fgf8a^x15/x15 WT + MO2-fgf10b + MO3-fgf10b fgf3^{t26212/t26212} + MO2-fgf10b + MO3-fgf10b fgf8a^x15/x15 + MO2-fgf10b + MO3-fgf10b (all 6)
Knockdown Reagents:	MO2-fgf10b MO3-fgf10b
Anatomical Term:	otic placode
Stage:	10-13 somites

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	fgf8a^x15/x15 WT + MO2-fgf10b + MO3-fgf10b fgf3^{t26212/t26212} + MO2-fgf10b + MO3-fgf10b fgf8a^x15/x15 + MO2-fgf10b + MO3-fgf10b
Knockdown Reagents:	MO2-fgf10b MO3-fgf10b
Observed In:	otic placode otic vesicle whole organism
Stage Range:	10-13 somites to Prim-5

Phenotype Detail

Acknowledgments

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