ZFIN ID: ZDB-FIG-141218-15
Krauss et al., 2013 - transparent, a gene affecting stripe formation in Zebrafish, encodes the mitochondrial protein Mpv17 that is required for iridophore survival. Biology Open   2(7):703-710 Full text @ Biol. Open
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Observed In:
Stage: Day 5

Fig. 6

transparent mutant iridophores display characteristics of apoptotic cells. EM sections of wild type (A) and transparent mutant iridophores (B) in the eye of 5 dpf larvae. (A) Wild type iridophores develop stacks of iridosomes nearly completely filling the cells. Iridosomes are not contrasted and appear empty as the guanine crystals are lost during the sectioning process (arrow). (B) Iridosomes are also visible in tra mutants. In the cell shown, only two iridosomes seem to contain guanine crystals (arrows), whereas others contain contrastable material (arrowhead), indicating that guanine deposition is not completed. Importantly and in contrast to wild type, tra mutant iridophores contain many vesicles, a sign for apoptosis. Scale bars: 0.5 mm.

Gene Expression DetailsNo data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
mpv17b18/b18 standard conditions Day 5 eye iridophore decreased amount, abnormal
Day 5 eye iridophore morphology, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Biology Open for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Biol. Open