FIGURE

Fig. S1

ID

ZDB-FIG-140903-41

Publication

Schiavone et al., 2014 - Zebrafish reporter lines reveal in vivo signaling pathway activities involved in pancreatic cancer

Other Figures

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Fig. S1

KRAS^G12D overexpression in zebrafish cerebellum induces medulloblastoma (MDB). A-D: Appearance of EGL (A) and 4th VZ (B) in normal cerebellum; zebrafish injected with KRAS^G12D develop early cerebellar lesions (C,D), which resemble medulloblastoma, starting from 15 dpf. E, F: Analysis of the histological features in 1 mpf zebrafish cerebellum reveals tumour masses (E) that resemble the classic type of human medulloblastoma (F) with sheets of small round blue cells with scant cytoplasm. (G) Schematic representation of a normal cerebellum, with EGL and VZ locations.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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