FIGURE

Fig. 3

ID

ZDB-FIG-140403-18

Publication

George et al., 2014 - Synaptojanin 1 is required for endolysosomal trafficking of synaptic proteins in cone photoreceptor inner segments

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Fig. 3

Large vesicular structures accumulate in nrc^a14 photoreceptor inner segments.

TEM images of cone photoreceptors in WT (A, B) and nrc^a14 (C?E) 5 dpf retinas. Large vesicular structures were visible in approximately 80% of nrc^a14 cone photoreceptor ISs. Some vesicular structures contained electron dense material (arrow heads, E). Boxes in A and C show areas enlarged in B and D respectively. Box in D shows area enlarged in E. OS = outer segment, N = nuclei. Scale bar = 2 μm in A?D, 1 μm in E.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	synj1^a14/a14
Observed In:	retinal cone cell cytoplasmic vesicle retinal cone cell photoreceptor inner segment
Stage:	Day 5

Phenotype Detail

Acknowledgments

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