Fig. 6
- ID
- ZDB-FIG-140313-33
- Publication
- Takke et al., 1999 - her4, a zebrafish homologue of the Drosophila neurogenic gene E(spl), is a target of notch signalling
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Flat preparations of 6-somite stage embryos injected with deltaD(Pst) RNA and stained for islet-1 expression by in situ hybridization (A-C). Arrows and asterisks label the affected side. (D,E) 1-somite stage embryos injected with deltaD(Pst) RNA and scored for ngn1 transcription, detected by in situ hybridization with a ngn1 probe (D) and by double staining for β-galactosidase (E). (F,G) 6- and 8- somite stage embryos, treated as in D and E. Inhibition of DELTA signalling leads to an activation of ngn1 transcription within the limits of its normal expression stripes. |