FIGURE

Fig. S4

ID

ZDB-FIG-140122-49

Publication

Kang et al., 2013 - Local dkk1 crosstalk from breeding ornaments impedes regeneration of injured male zebrafish fins

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Fig. S4

Additional Confocal Images of dkk1b:EGFP Expression During Fin Regeneration

(A) dkk1b:EGFP is low or undetectable at 2 dpa (blastema formation). (B) dkk1b:EGFP expression during female pectoral fin (left) and male (right) caudal fin regeneration at 4 dpa (regenerative outgrowth). dkk1b:EGFP is expressed in a small cluster of cells located in and near the distal-most regions of the blastema Kang, page 6 (arrows) at 4 dpa, and in areas of osteoblast patterning. Note that dkk1b:EGFP expression is associated with non-proliferative (BrdU+) regions. Amputation sites are proximal to imaged areas in (B). (C) High-magnification view of the distal tips of regenerating fins at 4 dpa. Brackets indicate a region of BrdU-low mesenchyme underlying the dkk1b:EGFP domain. Green: EGFP immunofluorescence; red: BrdU immunofluorescence; blue: DAPI. Scale bars = 50 μm (A, B); 10 μm (C)

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Cell, 27(1), Kang, J., Nachtrab, G., and Poss, K.D., Local dkk1 crosstalk from breeding ornaments impedes regeneration of injured male zebrafish fins, 19-31, Copyright (2013) with permission from Elsevier. Full text @ Dev. Cell