FIGURE
Fig. S6
- ID
- ZDB-FIG-131202-3
- Publication
- Nishiguchi et al., 2013 - Whole genome sequencing in patients with retinitis pigmentosa reveals pathogenic DNA structural changes and NEK2 as a new disease gene
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Fig. S6
In vivo functional evaluation of nek2 and rpgr deficiency in zebrafish. (A) Ocular phenotypes are quantified in control, nek2 MO, rpgr MO, and nek2 MO + rpgr MO embryos at full and sub-effective doses. (B) Immunohistochemical analyses of retinal cryosections from control, nek2 MO, rpgr MO, and nek2 + rpgr MO embryos at sub- effective doses, stained with DAPI (blue) and 4D2 antibody (green). Asterisk denotes excessive rhodopsin in the outer nuclear layer (ONL). OS, outer segment of photoreceptors; INL, inner nuclear layer. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Knockdown Reagents: | |
| Observed In: | |
| Stage: | Day 5 |
Phenotype Detail
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Full text @ Proc. Natl. Acad. Sci. USA