FIGURE

Fig. 3

ID

ZDB-FIG-130910-22

Publication

Kim et al., 2013 - Multi-organ Abnormalities and mTORC1 Activation in Zebrafish Model of Multiple Acyl-CoA Dehydrogenase Deficiency

Other Figures

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Fig. 3

Kidney defects in 8 dpf dxa^vu463 mutant zebrafish.

(A) Toluidine blue staining in pre-TEM sections at 8 dpf. Various sized vacuoles were observed in the dxa mutants. (B) ORO staining showing marked increase in lipids in dxa mutants. (C) TEM of kidney epithelium in wild type (left) and dxa mutants (right). Green colored regions indicate rod-shaped mitochondria in the kidney. (D) Filipin staining again shows free cholesterol accumulation in the cytosol of kidney cells. N, nuclei. Scale bar = 50 μm (A, B, D) and 2 μm (C).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	etfa^vu463/vu463
Observed In:	kidney kidney mitochondrion
Stage:	Days 7-13

Phenotype Detail

Acknowledgments

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