Fig. S1
- ID
- ZDB-FIG-130830-14
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- Dray et al., 2013 - Cell-Fibronectin Interactions Propel Vertebrate Trunk Elongation via Tissue Mechanics
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Analyses of Convergence Extension, Apoptosis, and Cell Proliferation in itgα5mo;αVmo Embryos, Related to Figure 1 (A) Wild-type, fn1mo;fn1bmo, itgα5mo;αVmo and Tg(tbx6l:itgα5-RFP);itgα5mo;αVmo embryos were fixed at the tailbud stage and in situ hybridization for her1 was performed. We then measured the medial-lateral width of the tailbud at the level of the posterior tip of the notochord. The fn1mo;fn1bmo embryos (n=30) exhibited a 17.5% increase in width of the tailbud (unpaired t-test; p-value <0.05) which is consistent with previous observations [1]. In contrast, neither itgα5mo;αVmo (n=37) nor Tg(tbx6l:itgα5-RFP);itgα5mo;αVmo embryos (n=24) displayed a change in tailbud width relative to wild type (n=55) (p-value >0.05). Error bars show standard error. The fn1 and fn1b morpholinos have been previously described [2]. |