FIGURE

Fig. S4

ID

ZDB-FIG-130828-19

Publication

Zhao et al., 2013 - Reptin/Ruvbl2 is a Lrrc6/Seahorse interactor essential for cilia motility

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Fig. S4

Reptin genetically interact with seahorse/lrrc6. (A) Reptin^hi2394; seahorse^hi3308 double mutants (double) show similar cystic kidney phenotype as single mutants of either gene at 4 dpf. (B) Percentage of embryos showing body curvature (Left) and kidney cysts (Right). A total of 89.3% embryos show kidney cyst formation and 94.1% embryos show body curvature in the reptin MO and seahorse MO coinjection group (rep+sea), compared with 1% cyst formation and body curvature in the seahorse MO and control MO coinjection group (sea) or 5.7% cyst formation and 6.2% body curvature in the reptin MO and control MO coinjection group (rep). Data are represented as mean + SD from three replicates. **P < 0.01.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	dnaaf11^{hi3308Tg/hi3308Tg} ruvbl2^{hi2394Tg/hi2394Tg} WT + MO1-dnaaf11 + MO1-ruvbl2 dnaaf11^{hi3308Tg/hi3308Tg}; ruvbl2^{hi2394Tg/hi2394Tg}
Knockdown Reagents:	MO1-dnaaf11 MO1-ruvbl2
Observed In:	post-vent region pronephros trunk
Stage:	Day 4

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA