ZFIN ID: ZDB-FIG-130129-36
Louwette et al., 2013 - NPC1 defect results in abnormal platelet formation and function: studies in Niemann-Pick disease type C1 patients and zebrafish. Human molecular genetics   22(1):61-73 Full text @ Hum. Mol. Genet.
Anatomical Terms:
Stage Range: 64-cell to Protruding-mouth
Knockdown Reagent:
Observed In:
Stage: Prim-5

Fig. 4 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
npc1 WT standard conditions 64-cell to Protruding-mouth whole organism RTPCR
Prim-5 brain ISH
Prim-5 eye ISH
Prim-5 yolk syncytial layer ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-npc1 standard conditions Prim-5 brain morphology, abnormal
Prim-5 eye morphology, abnormal
Prim-5 head malformed, abnormal
Prim-5 programmed cell death increased occurrence, abnormal
Prim-5 regulation of cholesterol storage disrupted, abnormal
Full text @ Hum. Mol. Genet.