FIGURE

Fig. 3

ID

ZDB-FIG-130115-26

Publication

Sakowski et al., 2012 - Neuromuscular effects of G93A-SOD1 expression in zebrafish

Other Figures

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Fig. 3

Activity monitoring in transgenic ALS zebrafish. (A): Representative experimental layout for monitoring spontaneous swimming behavior of 20 week old control (wells 1-3) and transgenic G93A-SOD1-GFP (wells 4-6) zebrafish using the Noldus Larvae Activity Monitoring System. (B) Movement tracks extrapolated from a 1 minute trial by EthoVision for analysis of multiple different activity parameters. (C) While minimal differences are observed in the spontaneous activity levels of transgenic and control zebrafish throughout the disease course, transgenic G93A-SOD1-GFP zebrafish exhibit a consistently lower swimming velocity relative to age-matched AB controls. (D) As the disease progresses, transgenic G93A-SOD1-GFP zebrafish spend more time resting than age-matched control AB zebrafish. * P < 0.01 compared to AB control slope.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	mi3021Tg (AB)
Observed In:	swimming swimming behavior
Stage Range:	Days 45-89 to Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Mol. Neurodegener.