FIGURE

Fig. 1

ID

ZDB-FIG-130115-11

Publication

Mellman et al., 2012 - Fibrillin-2b regulates endocardial morphogenesis in zebrafish

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Fig. 1

The scotch tape phenotype includes both a fin and a heart defect. Transmitted light images (A)-(D) show that the sco^te382 phenotype is visible by 24 hpf (A) and (B) and becomes clearer by 48 hpf (C) and (D). The caudal and dorsal fin fold defects manifest as a failure of the fin folds to expand, leading to a jagged appearance ((B), (D), black arrows) when compared to wild-type siblings (A) and (C). The heart defect can be accompanied by pronounced pericardial edema ((D), white arrow). Scale bars: (A) and (B), 0.5 mm; (C) and (D): 1 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	fbn2b^{te382a/te382a}; pku300^{te382b/te382b}
Observed In:	caudal fin dorsal fin fold pericardium
Stage Range:	Prim-5 to Long-pec

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 372(1), Mellman, K., Huisken, J., Dinsmore, C., Hoppe, C., and Stainier, D.Y., Fibrillin-2b regulates endocardial morphogenesis in zebrafish, 111-119, Copyright (2012) with permission from Elsevier. Full text @ Dev. Biol.