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Research
General Information
ZIRC
ZFIN ID: ZDB-FIG-130110-1
Pereboom et al., 2011 - A zebrafish model of dyskeratosis congenita reveals hematopoetic stem cell formation failure due to ribosomal protein-mediated p53 stabilization. Blood   118(20):5458-65 Full text @ Blood
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Fish:
Anatomical Term:
Stage: Day 4
PHENOTYPE:
Fish:
Observed In:
Stage Range: Prim-5 to Day 4

Fig. 1 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
nop10 WT standard conditions Day 4 whole organism RTPCR
nop10hi2578Tg standard conditions Day 4 whole organism RTPCR
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
nop10hi2578Tg/hi2578Tg standard conditions Prim-5 midbrain hindbrain boundary morphology, abnormal
Day 4 eye decreased size, abnormal
Day 4 gut immature, abnormal
Day 4 head decreased size, abnormal
Day 4 liver immature, abnormal
Day 4 pericardium edematous, abnormal
Day 4 ribosomal small subunit assembly disrupted, abnormal
Day 4 rRNA processing disrupted, abnormal
Day 4 swim bladder uninflated, abnormal
Full text @ Blood