FIGURE

Fig. 3

ID

ZDB-FIG-121212-21

Publication

Dumortier et al., 2012 - Collective mesendoderm migration relies on an intrinsic directionality signal transmitted through cell contacts

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Fig. 3

E-cadherin, Dsh/PCP, and Rac1 are required for cell orientation. Cells injected with Lifeact-mCherry RNAs and a control morpholino (A and B), E-cadherin morpholino (C and D), DshDep+ RNAs (E and F), or DN-Rac1 RNAs (G and H) were transplanted from shield to shield in Tg(gsc:GFP) embryos. Transplanted cells are within the prechordal plate (assessed by GFP expression), and contour of the plate is delineated (white line) when visible in the frame. Orientations of their cytoplasmic extensions were measured relative to the animal pole and plotted as histograms (B, D, F, and H) or cumulative plot (J). Frequencies of cytoplasmic extensions are also plotted (I).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA