header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-FIG-121130-3
Tsetskhladze et al., 2012 - Functional assessment of human coding mutations affecting skin pigmentation using zebrafish. PLoS One   7(10):e47398 Full text @ PLoS One
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Observed In:
Stage: Long-pec

Fig. 4 Effect of a human coding polymorphism on zebrafish mRNA rescue of the golden phenotype.

Lateral views of 48-hpf (A and B) wt zebrafish larva (C and D) golb1 zebrafish larva (E and F) golb1 larva injected with full-length zebrafish slc24a5 (wt) mRNA (500 pg) and (G and H) golb1 larva injected with full-length zebrafish slc24a5 mRNA with a single nucleotide change (500 pg), coding for the orthologous human derived A111T allele. Scale bars in (A, C, E, G) 150 μm, (B, D, F, H) 400 μm.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
slc24a5b1/b1 standard conditions Long-pec melanocyte absent, abnormal
Acknowledgments:
ZFIN wishes to thank the journal PLoS One for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ PLoS One