ZFIN Fish: slc24a5^b1/b1

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ZFIN ID: ZDB-FISH-150901-19447

Fish name:	slc24a5^b1/b1
Genotype:	slc24a5^b1/b1
Targeting Reagent:	none

HUMAN DISEASE MODELED by slc24a5^b1/b1

Human Disease	Conditions	Citations
bone inflammation disease	bacterial treatment by injection: Escherichia coli K-12	Nguyen-Chi et al., 2014

GENE EXPRESSION
Gene expression in slc24a5^b1/b1

RNA expression

Expressed Gene	Structure	Conditions	Figures
etv4	anterior lateral line placode blastomere diencephalon anterior region epiphysis eye forebrain forebrain neural plate heart tube hindbrain neural plate immature eye lateral line primordium lens epithelium margin Mauthner neuron midbrain ventral region midbrain hindbrain boundary middle lateral line placode otic vesicle paraxial mesoderm pectoral fin bud pharyngeal arch 3-7 proctodeum anatomical region Rohon-Beard neuron shield somite tail bud telencephalon anterior region trunk vent anatomical region	standard conditions	Fig. 2 from Münchberg et al., 1999
etv5b	blastomere diencephalon epiphysis eye forebrain forebrain neural plate hindbrain neural plate immature eye margin midbrain hindbrain boundary otic vesicle paraxial mesoderm pectoral fin bud pharyngeal arch 3-7 post-vent region radial glial cell retina rhombomere 1 rhombomere 2 rhombomere 3 rhombomere 4 rhombomere 5 rhombomere 6 shield somite tail bud telencephalon trunk	standard conditions	Fig. 1 from Münchberg et al., 1999
slc24a5	whole organism	control	Fig. 5 from Anastasaki et al., 2011
urp2	floor plate neural tube spinal cord anterior region	standard conditions	Fig. 4 from Parmentier et al., 2011

Protein expression

Antibody	Antigen Genes	Structure	Conditions	Figures
Ab1-tuba		Kupffer's vesicle cilium	control	Fig. 4 from Simms et al., 2012
Ab1-prkcz		Kupffer's vesicle apical plasma membrane	control	Fig. 4 from Simms et al., 2012

Reporter gene expression No data available

PHENOTYPE
Phenotype in slc24a5^b1/b1

Phenotype	Conditions	Figures
anal fin has fewer parts of type melanocyte, abnormal	standard conditions	Fig. 7 from Haffter et al., 1996
melanocyte absent, abnormal	standard conditions	Fig. 4 from Tsetskhladze et al., 2012
melanophore stripe decreased pigmentation, abnormal	standard conditions	Fig. 5 from Haffter et al., 1996
retinal pigmented epithelium melanosome decreased pigmentation, abnormal	standard conditions	Fig. 5 from Dooley et al., 2013

CITATIONS (42)

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