FIGURE

Fig. 5

ID

ZDB-FIG-121029-3

Publication

Ni et al., 2012 - Conditional control of gene function by an invertible gene trap in zebrafish

Other Figures

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Fig. 5

Phenotype of liver-specific supv3l1 inactivation. (A–D) Confocal images of the Left (A and B) and Right (C and D) sides of 21-d-old LiPan (A and C) and LiPan/supv3l1^LKO (B and D) fish showing detached hepatocytes (white arrows) (B and D) and smaller right liver lobe (white arrow) in supv3l1^LKO fish (D). (E and F) Histological analysis of wild-type (E) and supv3l1^LKO (F) fish indicate disorganized liver with dead cells (arrowhead) but normal intestinal lumen (black arrows) in supv3l1^LKO fish (F). (F) Survival curve of supv3l1^LKO fish (lens YFP⁺) compared with supv3l1^GtNf/GtNf siblings (lens YFP^-) during the first 6 wk of life. One group was fed a larval diet until 28 dpf followed by a juvenile diet (red) and the other group was kept on the larval diet (blue). (G) Photograph of a wild-type and a supv3l1^LKO mutant at 5 wk of age showing the smaller size of the mutant.

Expression Data

Gene:	DsRed
Fish:	gz15Tg
Anatomical Term:	liver
Stage:	Days 21-29

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	supv3l1^{vu497Gt/vu497Gt}; gz15Tg; s955Tg
Observed In:	hepatocyte liver whole organism
Stage:	Days 21-29

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA