FIGURE

Fig. 6

ID

ZDB-FIG-121025-45

Publication

Ben Shoham et al., 2012 - S1P1 inhibits sprouting angiogenesis during vascular development

Other Figures

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Fig. 6

s1p₁ MO embryos exhibit remodeling defects in the ISV and CVP. (A) Schematic showing the anatomical location of the areas shown in B and C. (B,C) Fluorescence microscopy of the ISV (B) and CVP (C) regions in WT and s1p₁ MO Tg(fli-egfp)^y1 zebrafish embryos at 24 and 48 hpf. (B2) Graph showing comparable filopodia numbers in ISV of WT and s1p₁ MO zebrafish (n_wt=11, n_s1p1MO=16, P=0.92). (C2) Graph showing comparison of the intercapillary area in the CVP between WT and s1p₁ MO zebrafish (n_wt=7, n_{s1p1 MO}=7, P=0.002, error bars represent s.e.m.). Scale bars: in B, 10 μm; in C, 20 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	y1Tg + MO2-s1pr1
Knockdown Reagent:	MO2-s1pr1
Observed In:	caudal vein plexus regulation of blood vessel remodeling
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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