FIGURE

Fig. 3

ID

ZDB-FIG-120810-30

Publication

Snyder et al., 2012 - Fbxw7 regulates Notch to control specification of neural precursors for oligodendrocyte fate

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Fig. 3

fbxw7 gene structure and expression. (A) Schematic representation of fbxw7 gene structure. Three alternative first exons, α, γ, and β, are spliced to exons 2–11. (B) Predicted amino acid sequences of Fbxw7 isoforms. The putative nuclear localization sequence of the α isoform is boxed. (C-F) Transverse sections through the level of the trunk spinal cord showing α and β-specific RNA expression detected by in situ hybridization. At 36 hpf, when pMN precursors initiate OPC formation, medial spinal cord cells α-fbxw7 at relatively high level whereas β-fbxw7 transcripts are only evident at low level in ventral spinal cord.

Expression Data

Gene:	fbxw7
Fish:	AB
Anatomical Terms:	glioblast (sensu Vertebrata) neural tube medial region neuroblast (sensu Vertebrata) spinal cord ventral region trunk spinal cord
Stage Range:	Prim-5 to Prim-25

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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