FIGURE

Fig. 2

ID

ZDB-FIG-120725-23

Publication

Chong et al., 2012 - STARS Is Essential to Maintain Cardiac Development and Function In Vivo via a SRF Pathway

Other Figures

All Figure Page

Back to All Figure Page

Fig. 2

Developmental phenotype of morpholino-induced knockdown of zSTARS: lateral views of 56 hpf embryos.

A. Embryo injected with control morpholino (with 5 mismatches). The cardiac silhouette is demarcated by arrowheads. The heart tube is looped so that the ventricle (v) and atrium (a) are closely apposed (inset). Circulating red blood cells (rbc) are visible in a thin rim along the inferior aspect of the yolk and within the heart. B. Embryo injected with zSTARS morpholino. The heart tube is unlooped so that the ventricle (v) and atrium (a) are co-linear, with atrial dilation (inset). There is significant edema in the pericardium and over the yolk, with stasis of red blood cells (rbc) over the yolk. C. Lateral view of entire 56 hpf embryo following injection of control, mismatch morpholino. D. and E. 56 hpf embryos showing representative phenotypes of zSTARS morpholino injection.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-abraa
Knockdown Reagent:	MO1-abraa
Observed In:	atrium blood blood circulation heart heart contraction heart looping pericardium sinus venosus somitogenesis whole organism apical-basal axis relative to substrate
Stage:	Long-pec

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One